CESAM chamber can be combined with the POLLURISK platform to expose living organisms to atmospheric pollutants (controlled mixtures). The key features of CESAM-POLLURISK are:

• Exposure of preclinical models to urban atmospheric pollution 

• Biological facility to conduct analysis on preclinical models (as an illustration lung function, systemic response, biological analyses, blood/urine/organs sampling, …

• Exposure of preclinical models to more complex exposome as noise and stress

• Measurement of associated Oxidative Potential of the simulated exposome

  • Exposure of cells/organoids in parallel to in vivo studies (starting 2025): in a nutshell, in vivo studies are dedicated to establish the links between Exposome components and Health Effects, when in vitro studies will contribute to identify the nature of these links.